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Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.

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Glycobiology of the Nervous System. Editors view affiliations Robert K. Front Matter Pages i-xvii. Pages Introduction to Cells Comprising the Nervous System. Synthesis, Processing, and Function of N-glycans in N-glycoproteins. Chemistry and Function of Glycosaminoglycans in the Nervous System. Glycosignaling: A General Review.

Neurobiology of Glycoconjugates by Margolis & R. K.

Glycosphingolipids in the Regulation of the Nervous System. Glycobiology of Ion Transport in the Nervous System. Martha C. Nowycky, Gusheng Wu, Robert W.

Neurobiology of Glycoconjugates - PDF Free Download

NMR Spectroscopy of Glycoconjugates. Neurobiology of Glycoconjugates structures and functions of glycoconjugates in the nervous system in the context of general bioedited by Richard U. Margolis and logical research. The topics are RenEe K. Margolis, Plenum Press, presented in an interesting way, Furthermore, that glycoproteins and glycolipids studies of glycoconjugate parare prominent constituents of ticipation in various processes, both the cell surface and the ranging from protein folding to extracellular matrix.

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Because of cellular interactions, are summartheir location, it has been repeat- ized in a manner that is both edly proposed that these mol- stimulating and accurate. This this field still has a long way to go.

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Furthermore, the Elements of Molecular existence of a large number of Neurobiology complex glycoconjugate structures suggests that they could by C. Because such interactions are Which elements currently constiparticularly important in the ner- tute the vaguely defined entity vous system, glycoconjugates termed 'molecular neurobiology'? This clear that molecular biological interest has been increased by a tools and approaches are emnumber of relevant observations. In addition, biologists for several decades.

When drawn tovolume, Complex Carbohydrates gether, they form a picture of a o f Nervous Tissue, which covered scientific field in full motion. This this area, and which is the pre- by itself makes this book a timely decessor to the present book. Much of this has resulted from Some of the difficulties may be general advances in cellular and bypassed by careful phrasing; molecular biology, which made for example, the choice of title for possible increasingly sophisticated this book clearly leaves space for work on the neurobiology of glyco- additions and changes.

Yet, the conjugates. Although some complementary proteins that bind glycoconjugates have been identified, it is likely that many more remain to be discovered; the biological consequences of their interactions with specific saccharides in the nervous system also remain to be determined.

So we can look forward, with great anticipation, to the next iteration of this book after another ten years. Extrapolating from the information gained between the first and second editions, we should really know a lot by then.